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Cas No. |
Product name |
11137608-69-5 |
Telotristat Etiprate (LX 1606 Hippurate) |
more... |
Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Phase 3 |
209984-57-6 |
LY411575 |
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LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch clevage with withIC50 of 0.39 nM |
471905-41-6 |
MK-0752 |
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MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2. |
1226056-71-8 |
Thiazovivin |
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Thiazovivin (Tzv) is a novel ROCK inhibitor with IC50 of 0.5 μM, promotes hESC survival after single-cell dissociation |
129830-38-2 |
Y27632 2hcl |
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Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, ... |
1342278-01-6 |
RKI-1447 |
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RKI-1447 is a potent inhibitor of ROCK1 and ROCK2, with IC50 of 14.5 nM and 6.2 nM, respectively, has anti-invasive and antitumor activities. |
850664-21-0 |
GSK269962A(GSK269962) |
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GSK269962A(GSK269962) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively); displays greater than 30-fold selectivity ... |
1192189-69-7 |
LX7101 HCL |
more... |
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105628-07-7 |
Fasudil (HA-1077) HCl |
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Fasudil (HA-1077) HCl is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM in cell-free assays, respectively. |
223645-67-8 |
K-115 (free base) |
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K-115 (free base) is a powerful selective ROCK inhibitor, IC50 values 31nM. |
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